The Athletics Integrity Unit (AIU) said Okagbare was banned for five years for the use of multiple prohibited substances and five for not co-operating with the investigation.
The 33-year-old was suspended during the Tokyo 2020 Olympics after failing a drug test.
- Pedri signs new Barca contract with 1 billion euro release clause
- Nigeria’s D’Tigers crash out of Tokyo 2020 Olympics
“The Disciplinary Tribunal has banned Nigerian sprinter Blessing Okagbare for a total of 10 years,” read an AIU statement.
“Five years for the presence and use of multiple prohibited substances and five years for her refusal to co-operate with the AIU’s investigation into her case.”
Brett Clothier, head of the AIU, said a 10-year ban was “a strong message against attempts to cheat”.
Okagbare won a silver medal in the long jump at the 2008 Olympics and has also won World Championship medals in the 200m and long jump.
She was a medal contender for the women’s 100m at last year’s Olympics and won her heat in 11.05 seconds.
But she was ruled out of the semi-finals after the AIU said she had tested positive for a human growth hormone following an out-of-competition test on 19 July.
In October, Okagbare was charged with three anti-doping offences, which she denied.
Okagbare has 30 days to appeal against the AIU’s disciplinary tribunal’s decision at the Court of Arbitration for Sport (CAS). (Complletesports)